Introducing Hydra-PEG Bio-Inspired Contact Lens Surfacing 

Our mission at Ocular Dynamics is to improve the comfort of contact lenses by applying a surface that mimics functional components of the natural tear film

Concept

Ocular Dynamics, low friction, protein Resistance, Tear Film Integration

Over 100 million patients worldwide wear contact lenses for vision correction. Despite innovation in the industry over the last 100 years, approximately 50% of patients still suffer from contact lens discomfort. In fact, this is the number one reason patients discontinue lens wear. The symptoms of contact lens discomfort are variable, but include; dryness, redness, itching, excess tearing and blurred vision.

The factors relating to contact lens comfort have been the center of some debate, however, it is generally accepted that the wettability, lubricity and protein resistance of lens surfaces, all play an important role in creating a comfortable patient experience. Hydra-PEG surfacing significantly improves all three of these properties and may be applied to rigid gas permeable, latheable silicone-hydrogel and disposable silicone-hydrogel lens types.

Wettability

Studies have shown that placing a contact lens on the eye increases the rate of tear evaporation from the ocular surface, therefore causing dryness. This is due to the poor interaction between lens materials and the water based surface of the eye.Hydra-PEG coating hides the core lens material, thus creating a highly wettable lens surface and preventing disruption of the tear film.

Bar graph showing tear evaporation rate increasing by 45% when wearing contact lens

The unique Hydra-PEG formulation is 90% water and therefore its material properties closely mimic those of the ocular surface and aqueous tear film. The table below demonstrates the significant improvement Hydra-PEG surfacing has on the wettability of several lens materials as measured by captive bubble advancing contact angle.

Hydra-PEG Captive Bubble

Lubricity

Lubricity of Hydra-PEG

The average person blinks 15,000 times per day. With the dynamic nature of the eye, the friction between the eyelid, contact lens and cornea, is an important factor in creating a comfortable lens surface. Hydra-PEG is extremely lubricious and yet allows for easy handling during insertion and removal. Studies have suggested that the frictional properties of contact lenses may also be associated with certain clinically observable phenomena, such as lid wiper epitheliopathy. The table to the right demonstrates the reduction in friction of Purevision (Bausch + Lomb) compared to the market leading Oasys (Johnson & Johnson).

Protein resistance

Hydra-PEG is extremely biocompatible, nontoxic, non-immunogenic, and resistant to protein deposition, which further aids in creating a comfortable lens surface. The main component in Hydra-PEG has been used in medical applications such as ocular medications, wound care products, and oral suspensions.  

Hydra-PEG Protein Resistance

About Ocular Dynamics

Ocular Dynamics is a venture funded, silicon valley based company founded in 2011.  For more information about how Hydra-PEG can improve your contact lens materials, contact us today!